4-(4-Tolyl)benzoic acid
4'-fluorobiphenyl-4-carboxylic acid
CAS: 5731-10-2;720-73-0
Molecular Formula: C13H9FO2
4-(4-Tolyl)benzoic acid - Names and Identifiers
| Name | 4'-fluorobiphenyl-4-carboxylic acid |
| Synonyms | AKOS B025023 AKOS BAR-0006 CHEMBRDG-BB 4400188 ART-CHEM-BB B025021 CHEMBRDG-BB 4400446 ART-CHEM-BB B025023 4-(4-Tolyl)benzoic acid 4-(4-FLUOROPHENYL)BENZOIC ACID 4'-Fluorobiphenyl-4-carboxylic acid 4'-METHYLBIPHENYL-4-CARBOXYLIC ACID 4'-fluorobiphenyl-4-carboxylic acid 4'-FLUORO-BIPHENYL-4-CARBOXYLIC ACID 4-BIPHENYL-4'-FLUORO-CARBOXYLIC ACID 4-METHYL-1,1-BIPHENYL-4-CARBOXYLIC ACID 4'-METHYL-1,1'-BIPHENYL-4-CARBOXYLIC ACID 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID [1,1'-Biphenyl]-4-carboxylic acid, 4'-fluoro- [1,1'-BIPHENYL]-4-CARBOXYLIC ACID, 4'-FLUORO- |
| CAS | 5731-10-2 720-73-0 |
| InChI | InChI=1/C13H9FO2/c14-12-7-5-10(6-8-12)9-1-3-11(4-2-9)13(15)16/h1-8H,(H,15,16) |
4-(4-Tolyl)benzoic acid - Physico-chemical Properties
| Molecular Formula | C13H9FO2 |
| Molar Mass | 216.21 |
| Density | 1.261±0.06 g/cm3(Predicted) |
| Melting Point | 235-240°C |
| Boling Point | 369.4±25.0 °C(Predicted) |
| Flash Point | 177.2°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 4.14E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 4.14±0.10(Predicted) |
| Storage Condition | -20°C Freezer |
| Refractive Index | 1.588 |
4-(4-Tolyl)benzoic acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| WGK Germany | 2 |
| Hazard Note | Irritant |
| Hazard Class | IRRITANT |
4-(4-Tolyl)benzoic acid - Introduction
4 '-fluorobiphenyl-4-carboxylic acid(4'-fluorobiphenyl-4-carboxylic acid) is an organic compound with the chemical formula C14H10FO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Properties: 4 '-fluorobiphenyl-4-carboxylic acid is a white or slightly yellow solid with a special aromatic odor. It has good solubility, high solubility in organic solvents such as ethanol, dimethylformamide and chloroform. The compound has a melting point of 135-137°C.
Uses: 4 '-fluorobiphenyl-4-carboxylic acid is commonly used as an intermediate in organic synthesis and pharmaceutical intermediates. It can be used for the synthesis of biologically active compounds, such as for the preparation of pesticides, pharmaceuticals and dyes. It can also be used for acylation reaction, substitution reaction and coupling reaction in organic synthesis reaction.
Preparation method: Most of the methods for preparing 4 '-fluorobiphenyl-4-carboxylic acid are through chemical synthesis. A commonly used synthetic method is the reaction of difluorobiphenyl and propionyl chloride, followed by defluorination under alkaline conditions to obtain the target product.
Safety information: 4 '-fluorobiphenyl-4-carboxylic acid has no reported hazard under normal operating conditions. However, like most chemicals, appropriate safety measures must be taken to avoid contact with skin and eyes, and to avoid inhalation or ingestion of the compound. Observe relevant safe operating instructions for use, storage and disposal.
Properties: 4 '-fluorobiphenyl-4-carboxylic acid is a white or slightly yellow solid with a special aromatic odor. It has good solubility, high solubility in organic solvents such as ethanol, dimethylformamide and chloroform. The compound has a melting point of 135-137°C.
Uses: 4 '-fluorobiphenyl-4-carboxylic acid is commonly used as an intermediate in organic synthesis and pharmaceutical intermediates. It can be used for the synthesis of biologically active compounds, such as for the preparation of pesticides, pharmaceuticals and dyes. It can also be used for acylation reaction, substitution reaction and coupling reaction in organic synthesis reaction.
Preparation method: Most of the methods for preparing 4 '-fluorobiphenyl-4-carboxylic acid are through chemical synthesis. A commonly used synthetic method is the reaction of difluorobiphenyl and propionyl chloride, followed by defluorination under alkaline conditions to obtain the target product.
Safety information: 4 '-fluorobiphenyl-4-carboxylic acid has no reported hazard under normal operating conditions. However, like most chemicals, appropriate safety measures must be taken to avoid contact with skin and eyes, and to avoid inhalation or ingestion of the compound. Observe relevant safe operating instructions for use, storage and disposal.
Last Update：2024-04-09 20:45:29
Supplier List
Multiple Specifications
Product Name: 4-Fluoro-Biphenyl-4-Carboxylic Acid Visit Supplier Webpage Request for quotationCAS: 5731-10-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: 4-Fluoro-Biphenyl-4-Carboxylic Acid Visit Supplier Webpage Request for quotationCAS: 5731-10-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History